Well the first thing I do is see what Spotlight is actually indexing upon un-suspending the Virtual Machine. This can be done from a Terminal using either of the following commands.
Note: Copy & Paste the command line into a Terminal so as not to mistype it. Because these command lines use sudo you'll need to type in your password for these to execute. Open a Terminal and copy and paste and start one of these commands just prior to un-suspending the Virtual Machine. (BTW This first commands syntax is actually sudo opensnoop -p PID where PID (Process ID) is of mdworker(or other program) and I've written the command so you do not first have to manually find the PID of mdworker.)
sudo opensnoop -p `ps -A | grep -m1 mdworker | awk '{print $1}'`
Or
sudo fs_usage -w -f filesys mdworker | egrep "open"
Once you see what's actually being indexed you can then attempt to make adjustments to the Spotlight Privacy settings in System Preferences.
